Systems Immunology & Immunotechnology

Yariv Wine, PhD.
Principal Investigator
Green Building, room 222
Molecular Microbiology and Biotechnology
Faculty of Life Sciences
Tel Aviv University
Ramat Aviv
Israel, 6997801
Tel: +972 3 6408723
Email: yarivwine@tauex.tau.ac.il

Yael Dror, Ms.c.
Labratory Manager
Green building, room 224
Molecular Microbiology and Biotechnology
Faculty of Life Sciences
Tel-Aviv University
Ramat-Aviv
Israel, 6997801
Tel: +972 3 640 7518
Fax: +972 3 640 5147
Email: Dror11@tauex.tau.ac.il
PhD. Students

Limor joined our group in Apr-2016 after completing her masters thesis at the Department of Molecular Microbiology and Biotechnology, Tel Aviv University.
During her PhD, Limor focus on the impact of pregnancy on the nature of the immune response following maternal immunization.
In her MSc studies, she developed an ex- vivo system for high-throughput analysis of molecular chaperon as therapeutic strategy for the von Hipple –Lindau cancer syndrome. She examined candidates to restore folding, stability and function of VHL Tumor Suppressor Protein.
Alongside her PhD research, Limor tutors future scientists from the ‘Tel Aviv University for youth’ that promotes young scientists to discover and research in the academy during mid and high school.

Shai Rosenstein
PhD. Student
Shai joined our group in Oct-2015 after completing her BSc. at the Faculty of Life Sciences, Tel Aviv University.
During her BSc. studies she worked as a research assistant in the Department of Zoology and in the Department of Molecular Microbiology and Biotechnology.
In her MSc. project Shai focused on the characterization of the antibodies elicited following infusion of anti-TNFa agent (Infliximab) to IBD patients. Specifically, Shai will look for associations between neutralizing anti drug antibodies and various cytokines (e.g. BAFF).

Aya joined our group in Oct-2017 after completing her BSc. at the Robert H. Smith faculty of agriculture, food and environment, Hebrew University of Jerusalem.
During her PhD, Aya focus on the molecular landscape of B cell immunity at the maternal-infant interface
In her MSc. project Aya focused on developing computational and experimental frameworks for proteomic analysis of serum antibodies.
Her PhD project involves the study of maternal immunization.

Ligal Aizik
PhD. Student
Joined on may-2019 after completing her BSc in Biotechnology at the faculty of Life Sciences, Tel Aviv University.
On her PhD project Ligal is working on characterizing the phenotype of tumor infiltrating B lymphocytes, tumor-associated B cells and their distinct antibody repertoire.
During her BSc she gained experience as research assistant in our lab, working on production, purification and validation of Tetanus Toxoid C fragment (rTTC), and purification of rTTC and TT-specific antibodies from pregnant women.
MSc. Students

Joined the WIne lab in October 2019 after completing his BSc. in Life Sciences in the Faculty of Life Sciences at Ben-Gurion University.
Focused his study and research on the longitudinal kinetics of the serological response in COVID-19 recovered patients over the period of 14 months with a comparison to the differences and effects in longitudinal kinetics between recovered patients, naïve BNT162b2 vaccinees and recovered patients post vaccination.

David joined our group in may-2020 after completing his BSc. in biomedical engineering at UAS Vienna,Austria. David's project involves the development of an enhanced screening method of semi-synthetic phage libraries using NGS after phage-panning.
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Camilla joined our group in October 2021 after completing BSc in biology at the faculty of life science, Sapienza University of Rome.
In her MSc Camilla is working on the dynamics of the vaccine-specific antibody response in breast milk.

Joined on October-2021 after completing her BSc in Biology at the faculty of Life Sciences, Tel Aviv University.
Talya's project is in the field of NGS and phage-panning.
During her BSc she gained experience as research assistant in our lab, working on vector cloning and human antibody expression.
Alumni

Anna joined our group in Oct-2014 after completing her masters thesis at the Department of Molecular Microbiology and Biotechnology. During her master she worked on developing an animal model for in-vivo restoration of p53 cancer associated mutations and the development of a novel method of examining p53 DNA binding. In addition to her thesis, Anna worked as a teacher assistant in the genetics lab course.
Anna earned her BSc. in biology at the Faculty of Life Sciences at Tel Aviv University. During her BSc. she gained experience as a research assistant in the Department of Neurobiology working on characterization of microglia activation in a novel Alzheimer's disease transgenic mice model. In her PhD. project Anna works on analyzing the drug-antibody repertoire in inflammatory bowel disease patients treated with Infliximab.
Yaron Hillman, PhD.
Research Associate
Yaron completed his PhD. (direct track) in Tel Aviv University, at the Department of Cell and Developmental Biology, Sackler faculty of Medicine, under the supervision of Prof. Zvi Fishelson. In his PhD. he was studying and characterizing microRNAs that modulate the sensitivity of cancer cells to complement-dependent cytotoxicity. During that time, he had worked as an instructor in the Histology and Embryology courses for medical students at the Sackler School of Medicine.
Yaron earned his B.Sc in Biology at the Faculty of Life Sciences. During his B.Sc studies, he had worked as a research assistant, investigating microRNA involvement in the regulation of amyloid precursor protein (APP) gene expression, in Alzheimer's disease transgenic mice model.
Yaron works on a novel therapeutic monoclonal antibody to combat multidrug-resistant (MDR) pathogenic bacteria.

Dan joined our group in Oct-2017 after completing his BSc. in Marine Biotechnology at the Ruppin Academic Center. During his BSc. Dan participated in a research project under the supervision of Dr. Nir Nesher & Dr. Tal Shomrat which focused on characterization of structure and anti-bacterial activity of Octopus vulgaris skin mucus.
Dan's current project involves the study of anti-bacterial immunotherapy.
Dan joined our group in Oct-2015 after completing his BSc.